Neville H. McClenaghan: search on Z-Library

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1

The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets

Catriona Kelly, Hong Guo Parke, Jane T. McCluskey, Peter R. Flatt, Neville H. McClenaghan

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

2

N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic β-cell-associated gene expression

Hui-Kang Liu, Brian D. Green, Victor A. Gault, Jane T. McCluskey, Neville H. McClenaghan, Finbarr P.M. O'Harte, Peter R. Flatt

Journal:

Cell Biology International

Year:

2004

Language:

english

File:

PDF, 93 KB

english, 2004

3

Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide

Neville H McClenaghan, Andrew J Ball, Peter R Flatt

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

4

Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4

Vasu, Srividya, McClenaghan, Neville H., McCluskey, Jane T., Flatt, Peter R.

Journal:

Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 817 KB

english, 2013

5

Improved antioxidative defence protects insulin-producing cells against homocysteine toxicity

Scullion, Siobhan M., Hahn, Claudine, Tyka, Karolina, Flatt, Peter R., McClenaghan, Neville H., Lenzen, Sigurd, Gurgul-Convey, Ewa

Journal:

Chemico-Biological Interactions

Year:

2016

Language:

english

File:

PDF, 1.89 MB

english, 2016

6

Mechanisms of action of cationic amino acids on insulin-secreting BRIN-BD11 cells

McCLENAGHAN, NEVILLE H., BARNETT, CHRISTOPHER R., FLATT, PETER R.

Journal:

Biochemical Society Transactions

Year:

1997

Language:

english

File:

PDF, 113 KB

english, 1997

7

Secretory properties of clonal insulin-secreting BRIN-BG5 cells, produced by electrofusion

McClenaghan, Neville H., Barnett, Christopher R., Ah-Sing, Eric, Swanston-Flatt, Sara K., FLATT, PETER R.

Journal:

Biochemical Society Transactions

Year:

1996

Language:

english

File:

PDF, 125 KB

english, 1996

8

The effects of protein kinase inhibitors on Type I diabetic serum-induced BRIN BD11 pancreatic beta-cell cytotoxicity

Dixon, Gordon, McClenaghan, Neville, Flatt, Peter, Nolan, John, Newsholme, Philip

Journal:

Biochemical Society Transactions

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

9

Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic β-cell insulin secretion, growth and functional integrity

DIXON, Gordon, NOLAN, John, McCLENAGHAN, Neville H., FLATT, Peter R., NEWSHOLME, Philip

Journal:

Clinical Science

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

10

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

Khan, Dawood, Kelsey, Ryan, Maheshwari, Rashmi R., Stone, Virginia M., Hasib, Annie, Manderson Koivula, Fiona N., Watson, Aoife, Harkin, Stephen, Irwin, Nigel, Shaw, James A., McClenaghan, Neville H.,

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.11 MB

english, 2019

11

Prolonged exposure to homocysteine results in diminished but reversible pancreatic β-cell responsiveness to insulinotropic agents

Steven Patterson, Siobhan M. J. Scullion, Jane T. McCluskey, Peter R. Flatt, Neville H. McClenaghan

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2007

Language:

english

File:

PDF, 296 KB

english, 2007

12

Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines

Neville H. McClenaghan, Peter R. Flatt

Journal:

Diabetes, Obesity and Metabolism

Year:

1999

Language:

english

File:

PDF, 635 KB

english, 1999

13

Effects of Long‐Term Exposure to Nicotinamide and Sodium Butyrate on Growth, Viability, and the Function of Clonal Insulin Secreting Cells

Liu, Hui‐Kang, Green, Brian D., Flatt, Peter R., McClenaghan, Neville H., McCluskey, Jane T.

Journal:

Endocrine Research

Year:

2004

Language:

english

File:

PDF, 228 KB

english, 2004

14

Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells

Green, Alastair D., Vasu, Srividya, McClenaghan, Neville H., Flatt, Peter R.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

15

Physiological regulation of the pancreatic β-cell: functional insights for understanding and therapy of diabetes

Neville H. McClenaghan

Journal:

Experimental Physiology

Year:

2007

Language:

english

File:

PDF, 834 KB

english, 2007

16

Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells

Catriona Kelly, Peter R. Flatt, Neville H. McClenaghan

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 490 KB

english, 2010

17

Determining the relationship between dietary carbohydrate intake and insulin resistance

McClenaghan, Neville H.

Journal:

Nutrition Research Reviews

Year:

2005

Language:

english

File:

PDF, 344 KB

english, 2005

18

Molecular Mechanisms of Toxicity and Cell Damage by Chemicals in a Human Pancreatic Beta Cell Line, 1.1B4

Vasu, Srividya, McClenaghan, Neville H., Flatt, Peter R.

Journal:

Year:

2016

Language:

english

File:

PDF, 774 KB

english, 2016

19

Homocysteine and other structurally-diverse amino thiols can alter pancreatic beta cell function without evoking cellular damage

Steven Patterson, Peter R. Flatt, Neville H. McClenaghan

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2006

Language:

english

File:

PDF, 314 KB

english, 2006

20

Prolonged L-alanine exposure induces changes in metabolism, Ca 2+ handling and desensitization of insulin secretion in clonal pancreatic β-cells

McClenaghan, Neville H., Scullion, Siobhan M., Mion, Brian, Hewage, Chandralal, Malthouse, J. Paul G., Flatt, Peter R., Newsholme, Philip, Brennan, Lorraine

Journal:

Clinical Science

Year:

2009

Language:

english

File:

PDF, 423 KB

english, 2009

21

Molecular Characterization of the Glucose-Sensing Mechanism in the Clonal Insulin-Secreting BRIN-BD11 Cell Line

Neville H. McClenaghan, Matthias Elsner, Markus Tiedge, Sigurd Lenzen

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 130 KB

english, 1998

22

Stimulation of insulin secretion in clonal BRIN-BD11 cells by the imidazoline derivatives KU14r and RX801080

Andrew J. Ball, Peter R. Flatt, Neville H. McClenaghan

Journal:

Pharmacological Research

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

23

Evaluation of the role of N-methyl-D-aspartate (NMDA) receptors in insulin secreting beta-cells

Patterson, Steven, Irwin, Nigel, Guo-Parke, Hong, Moffett, R. Charlotte, Scullion, Siobhan M., Flatt, Peter R., McClenaghan, Neville H.

Journal:

European Journal of Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

24

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism

Lorraine Brennan, Chandralal Hewage, J. P. G. Malthouse, Neville H. McClenaghan, Peter R. Flatt, Philip Newsholme

Journal:

Year:

2006

Language:

english

File:

PDF, 238 KB

english, 2006

25

Desensitization of sulphonylurea- and nutrient-induced insulin secretion following prolonged treatment with glibenclamide

Andrew J Ball, Peter R Flatt, Neville H McClenaghan

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 343 KB

english, 2000

26

Chronic exposure to tolbutamide and glibenclamide impairs insulin secretion but not transcription of KATP channel components

Andrew J Ball, Jane T McCluskey, Peter R Flatt, Neville H McClenaghan

Journal:

Pharmacological Research

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004

27

A stable analogue of glucose-dependent insulinotropic polypeptide, GIP(LysPAL16), enhances functional differentiation of mouse embryonic stem cells into cells expressing islet-specific genes and hormones

Marenah, Lamin, McCluskey, Jane T., Abdel-Wahab, Yasser H.A., O'Harte, Finbarr P.M., McClenaghan, Neville H., Flatt, Peter R.

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

28

Induction of a Glucose-Dependent Insulin Secretory Response by the Nonmetabolizable Amino Acid α-Aminoisobutyric Acid

McClenaghan, Neville, Berts, Alf, Dryselius, Staffan, Grapengiesser, Eva, Saha, Samir, Hellman, Bo

Journal:

Year:

1997

Language:

english

File:

PDF, 446 KB

english, 1997

29

Drug-Induced Desensitization of Insulinotropic Actions of Sulfonylureas

Andrew J. Ball, Jane T. McCluskey, Peter R. Flatt, Neville H. McClenaghan

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 156 KB

english, 2000

30

Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells

McKiney, Joan M., Irwin, Nigel, Flatt, Peter R., Bailey, Clifford J., McClenaghan, Neville H.

Journal:

Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

31

Cellular responses of novel human pancreatic β-cell line, 1.1B4 to hyperglycemia

Vasu, Srividya, McClenaghan, Neville H, McCluskey, Jane T, Flatt, Peter R

Journal:

Year:

2013

Language:

english

File:

PDF, 512 KB

english, 2013

32

Effect of glucose and amino acids on insulin-secretion from a novel pancreatic B-cell line produced by electrofusion

McCLENAGHAN, NEVILLE H., YOON, TAI-WOOK, BARNETT, CHRISTOPHER R., WILSON, ALISON M., ABDEL-WAHAB, YASSER H. A., SWANSTON-FLATT, SARA, AH-SING, ERIC, FLATT, PETER R.

Journal:

Biochemical Society Transactions

Year:

1994

Language:

english

File:

PDF, 110 KB

english, 1994

33

Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide

Andrew J. Ball, Peter R. Flatt, Neville H. McClenaghan

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 137 KB

english, 2005

34

Engineering of a Glucose-Responsive Surrogate Cell for Insulin Replacement Therapy of Experimental Insulin-Dependent Diabetes

Tiedge, Markus, Elsner, Matthias, McClenaghan, Neville Hugo, Hedrich, Hans-Jurgen, Grube, Dietrich, Klempnauer, Jurgen, Lenzen, Sigurd

Journal:

Human Gene Therapy

Year:

2000

Language:

english

File:

PDF, 462 KB

english, 2000

35

Islet-intrinsic effects ofCFTRmutation

Koivula, Fiona N. Manderson, McClenaghan, Neville H., Harper, Alan G. S., Kelly, Catriona

Journal:

Year:

2016

Language:

english

File:

PDF, 461 KB

english, 2016

36

Stem Cell-Based Approaches for the Treatment of Diabetes

Kelly, Catriona, Flatt, Cara C. S., McClenaghan, Neville H.

Journal:

Stem Cells International

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

37

Role of islet structure and cellular interactions in the control of insulin secretion

Kelly, Catriona, McClenaghan, Neville H., Flatt, Peter R.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.94 MB

english, 2011

38

Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity

Vasu, Srividya, Moffett, R. Charlotte, McClenaghan, Neville H., Flatt, Peter R.

Journal:

Experimental Cell Research

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

39

Acute and long-term effects of nateglinide on insulin secretory pathways

Andrew J Ball, Peter R Flatt, Neville H McClenaghan

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

40

Specific desensitization of sulfonylurea- but not imidazoline-induced insulin release after prolonged tolbutamide exposure

Neville H. McClenaghan, Andrew J. Ball, Peter R. Flatt

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 682 KB

english, 2001

41

Comparison of Insulin Release From MIN6 Pseudoislets and Pancreatic Islets of Langerhans Reveals Importance of Homotypic Cell Interactions

Kelly, Catriona, Guo, Hong, McCluskey, Jane T., Flatt, Peter R., McClenaghan, Neville H.

Journal:

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

42

Glucose and non-glucidic nutrients exert permissive effects on 2-keto acid regulation of pancreatic β-cell function

Neville H McClenaghan, Peter R Flatt

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1999

Language:

english

File:

PDF, 527 KB

english, 1999

43

Insulin-releasing action of the novel antidiabetic agent BTS 67 582

Neville H. McClenaghan, Peter R. Flatt, Clifford J. Bailey

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 322 KB

english, 1998

44

Na+Cotransport by Metabolizable and Nonmetabolizable Amino Acids Stimulates a Glucose-Regulated Insulin-Secretory Response

Neville H. McClenaghan, Christopher R. Barnett, Peter R. Flatt

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 125 KB

english, 1998

45

Hexose Recognition by Insulin-Secreting BRIN-BD11 Cells

Neville H. McClenaghan, Alison M. Gray, Christopher R. Barnett, Peter R. Flatt

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 73 KB

english, 1996

46

Major metabolic homocysteine-derivative, homocysteine thiolactone, exerts changes in pancreatic β-cell glucose-sensing, cellular signal transduction and integrity

Steven Patterson, Peter R. Flatt, Neville H. McClenaghan

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 394 KB

english, 2007

47

Correction to: Islet-intrinsic effects of CFTR mutation

Manderson Koivula, Fiona N., McClenaghan, Neville H., Harper, Alan G. S., Kelly, Catriona

Journal:

Year:

2017

Language:

english

File:

PDF, 273 KB

english, 2017

48

Glycine transformation of Ca2+ oscillations into a sustained increase parallels potentiation of insulin release

Anders Tengholm, Neville McClenaghan, Eva Grapengiesser, Erik Gylfe, Bo Hellman

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1992

Language:

english

File:

PDF, 287 KB

english, 1992

49

Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4

Vasu, Srividya, McClenaghan, Neville H., McCluskey, Jane T., Flatt, Peter R.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

50

L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic β-cell line and protects from pro-inflammatory cytokine-induced apoptosis

Cunningham, Grainne A., Mcclenaghan, Neville H., Flatt, Peter R., Newsholme, Philip

Journal:

Clinical Science

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

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